How does Botox work?
Botox is comprised of a naturally-occurring, purified protein. Botox safely and temporarily blocks nerve impulses from entering the muscle to reduce it’s activity. When a muscle is no longer contracting, it reduces the wrinkling you would normally see when making an expression.
In addition to treating wrinkles, Botox can be used to create facial symmetry or for facial shaping. Common areas for Botox treatment include elevating the brow, jawline slimming, reduction of TMJ pain, reversing downturned lips or a downturned nasal tip, uneven eye size or a “jelly roll” under the eye, correcting a “gummy smile” or “bunny lines”, and reducing neck bands.
Expert knowledge of facial anatomy is the key to outstanding results. Precise dose and placement determine success of the treatment. Dr. Cox has performed multiple clinical trials for Botox right here in Chapel Hill, and travels frequently teaching other physician’s best injection practice and how to avoid complications.
Is Botox safe?
The FDA has approved Botox to safely treat wrinkles. Like any surgical or non-surgical procedure, there are risks. As an international teacher and trainer of other physicians in facial anatomy and injection technique, Dr. Cox stresses the importance of finding an experienced physician who understands the finer points of injectable treatments. Dr. Cox performed clinical trials for Botox as well as new neuromodulators not yet on the market and is internationally recognized for her skills as an injector.
Botox treatments are well tolerated. The treatment is comprised of a series of precise injections with a very small needle. This process only takes a few minutes. Patients often compare the feeling to having their eyebrows plucked.
There is no downtime associated with Botox. Once the injections are complete, there is typically mild swelling and redness around the pin-prick injection sites. This dissipates within a few minutes.
You will begin to see results from Botox within three to four days. Full results will appear two weeks after treatment. Botox typically last three to four months. One Botox treatment will reduce or eliminate dynamic wrinkles in the treatment area. Wrinkles that are etched in (remain visible at rest) will need multiple sessions for optimal results. In the case of etched lines, additional treatment modalities may be needed.
Related Clinical Trials
Dr. Cox was principal investigator for the study “A Placebo Controlled Study to Assess Patient-Reported Outcomes in Subjects Receiving BOTOX (Botulinum Toxin Type A) for Treatment of Moderate to Severe Glabellar Rhytids.” The study was performed April to December 2005.
Dr. Cox was principal investigator for the study “Prospective, Double-Blind, Randomized, Parallel Group, Dose-Ranging Study of Botox in Female Subjects with Vertical Lip Lines.” The study was performed in January 2008.
Dr. Cox was principal investigator for the study “A Pilot Study of BOTOX® Cosmetic in the Treatment of Moderate to Severe Glabellar Lines – Establishing Patient Satisfaction.” The study was performed in May 2011.
Dr. Cox was principal investigator in the study “A Pilot Study of BOTOX® Cosmetic in the Treatment of Moderate to Severe Glabellar Lines – Establishing Patient Satisfaction.” The study was performed to assess patient satisfaction of treatment for wrinkles between the brows. The study was conducted October through December 2012.
Dr. Cox finished work as the principal investigator for this study “A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study on the Safety and Pharmacodynamic Response of BOTOX in Subjects with Moderate to Severe Dynamic Glabellar Lines.” The study evaluated tweaks in the treatment of moderate to severe glabellar lines (those vertical lines between the brow). Dr. Cox enjoyed looking at an existing product with a new perspective. This study began in November of 2017 and ended in March of 2019.